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KMID : 1004520240400010001
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Journal of Dental Rehabilitation and Applied Science
2024 Volume.40 No. 1 p.1 ~ p.12
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Effect of calcium silicate-based sealer to bone tissue of mandible of rats
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Tae Jee-Seon
Yoo Ki-Yeon
Kim Jin-Woo
Cho Kyung-Mo
Lee Yoon
Park Se-Hee
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Abstract
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Purpose: To histologically evaluate the effects of three calcium silicate-based sealers on rat mandible tissue.
Materials and Methods: Rats were randomly divided as follows: A group that sacrificed immediately after cavity preparation, a group that sacrificed two weeks after cavity preparation, a group that sacrificed two weeks after CeraSeal (CS), AH Plus Bioceramic (AHB), or One-Fil (OF) sealer injection, respectively. After tissue processing for all groups, the bone tissue area (%) and the number of osteoclasts in and around the cavity were measured under a microscope. The results of each group were compared and statistical analysis was performed using one-way ANOVA and Tukey’s test.
Results: The formation of bone tissue and the presence of osteoclasts in the cavity were observed in the group that sacrificed two weeks after cavity preparation and the group sacrificed two weeks after AHB sealer injection, and these groups showed significantly higher average bone tissue area (%) than the other groups. In the other groups, no inflammation or foreign body reaction occurred in the cavity, and no osteoclasts were observed.
Conclusion: All calcium silicatebased sealers used in this study showed a favorable bone tissue response when injected into the rat mandible. In particular, higher bone formation in the cavity was observed in AHB.
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KEYWORD
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bone regeneration, bone tissue area, calcium silicate-based sealer, osteoclast
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